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They also contain a lot of antioxidants and a decent amount of polyunsaturated fatty acids, potassium, vitamin B2 (riboflavin) and folate. Pumpkin seeds and seed oil also pack many other nutrients and plant compounds that have been shown to provide health benefits. Pumpkin seeds contain antioxidants like carotenoids and vitamin E. Antioxidants can reduce inflammation and protect your cells from harmful free radicals. That’s why consuming foods rich in antioxidants can help protect against many diseases. It’s thought that the high levels of antioxidants in pumpkins seeds are partly responsible for their positive effects on health. In one study, pumpkin seed oil reduced inflammation in rats with arthritis without side effects, whereas animals given an anti-inflammatory drug experienced adverse effects.